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Artocarmins G–M, Prenylated 4-Chromenones from the Stems of Artocarpus rigida and Their Tyrosinase Inhibitory Activities
Journal of Natural Products ( IF 5.1 ) Pub Date : 2017-12-11 00:00:00 , DOI: 10.1021/acs.jnatprod.7b00453
Mai T. T. Nguyen , Tho H. Le , Hai X. Nguyen , Phu H. Dang , Truong N. V. Do , Manabu Abe 1 , Ryukichi Takagi 1 , Nhan T. Nguyen
Affiliation  

Phytochemical analysis of an EtOAc extract of the stems of Artocarpus rigida led to the identification of seven new prenylated 4-chromenones, artocarmins G–M (17), and nine known compounds (817). Their structures were identified based on physical data analysis. In the tyrosinase inhibitory activity test, norartocarpetin (8) displayed the strongest effect, with an IC50 value of 0.023 μM.

中文翻译:

Artocarmins G-男,异戊烯基4-Chromenones从茎桂杜松及其酪氨酸酶抑制活性

的一个EtOAc萃取物的植物化学分析茎桂杜松导致的七个新异戊二烯化4- chromenones,artocarmins G-M(标识17),和九种已知化合物(8 - 17)。根据物理数据分析确定了它们的结构。在酪氨酸酶抑制活性测试中,去甲肾上腺素(8)表现出最强的作用,IC 50值为0.023μM 。
更新日期:2017-12-11
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