Ag-/Au-NiCo₂O₄ nanosheets were synthesized by a facile electrodeposition approach on conducting Ni foam, and their non-enzymatic glucose sensing performance was investigated. The hybrid nanosheets of NiCo₂O₄ and noble-metal nanoparticles supported on conductive Ni foam possessed high active surface area along with intrinsic electrocatalytic and biocatalytic properties and promoted electronic/ionic transport in the electrodes, leading to improved glucose sensing properties. The sensitivity of the bare NiCo₂O₄ nanosheets for electrochemical non-enzymatic glucose sensing was 20.8 μA μM⁻¹ cm⁻², whereas the NiCo₂O₄-Ag and NiCo₂O₄-Au nanosheet electrodes exhibited enhanced sensitivities of 29.86 and 44.86 μA μM⁻¹ cm⁻², respectively, with lower response times in the same linear range of 5–45 μM. We also performed density functional theory simulations to corroborate our experimental observations by investigating the interactions and charge-transfer mechanism of glucose on Ag- and Au-doped NiCo₂O₄. As Au is bound more strongly to the NiCo₂O₄ surface compared to Ag, the binding energy of glucose is greater on the Au-doped NiCo₂O₄ surface than on the Ag-doped NiCo₂O₄ surface, and Au doping makes NiCo₂O₄ more conductive compared to Ag doping. Thus, it can be theoretically inferred that Au-doped NiCo₂O₄ has better glucose sensing performance, which supports our experimental data.

中文翻译：

---

Ag- / Au-NiCo ₂ O ₄纳米片具有卓越的非酶促葡萄糖感测特性，并具有电子结构仿真的结果†

通过一种简便的电沉积方法在导电Ni泡沫上合成了Ag- / Au-NiCo ₂ O ₄纳米片，并研究了它们的非酶促葡萄糖传感性能。NiCo ₂ O ₄和负载在导电Ni泡沫上的贵金属纳米颗粒的杂化纳米片具有高的活性表面积以及固有的电催化和生物催化特性，并促进了电极中的电子/离子迁移，从而改善了葡萄糖感测特性。裸露的NiCo ₂ O ₄纳米片对电化学非酶法葡萄糖感测的灵敏度为20.8μAμM - ¹ cm ^-2，而NiCo ₂O ₄ -Ag和NiCo ₂ O ₄ -Au纳米片电极分别具有29.86和44.86μAμM ^-1 cm ^-2的增强灵敏度，在相同的5–45μM线性范围内具有较低的响应时间。我们还通过研究葡萄糖在Ag和Au掺杂的NiCo ₂ O ₄上的相互作用和电荷转移机理，进行了密度泛函理论模拟，以证实我们的实验观察结果。由于与Ag相比，Au与NiCo ₂ O ₄表面的结合更牢固，因此与Au掺杂的NiCo相比，Au掺杂的NiCo ₂ O ₄表面的葡萄糖的结合能更大。₂ O ₄表面，Au掺杂使NiCo ₂ O _4的导电性高于Ag掺杂。因此，从理论上可以推断金掺杂的NiCo ₂ O ₄具有更好的葡萄糖感测性能，这支持了我们的实验数据。