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The PAQosome, an R2TP-Based Chaperone for Quaternary Structure Formation
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2017-12-05 , DOI: 10.1016/j.tibs.2017.11.001
Walid A. Houry , Edouard Bertrand , Benoit Coulombe

The Rvb1–Rvb2–Tah1–Pih1/prefoldin-like (R2TP/PFDL) complex is a unique chaperone that provides a platform for the assembly and maturation of many key multiprotein complexes in mammalian cells. Here, we propose to rename R2TP/PFDL as PAQosome (particle for arrangement of quaternary structure) to more accurately represent its unique function.



中文翻译:

PAQosome,用于四级结构形成的基于R2TP的伴侣

Rvb1-Rvb2-Tah1-Pih1 / prefoldin-like(R2TP / PFDL)复合物是独特的分子伴侣,为哺乳动物细胞中许多关键的多蛋白复合物的组装和成熟提供了平台。这里,我们提出以重命名R2TP / PFDL作为PAQosome(p为第一个的rrangement q uaternary结构),以更精确地表示其特有的功能。

更新日期:2017-12-05
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