Axially chiral P,N-ligands have emerged as a powerful ligand class over time with significant recent advances in terms of their synthesis, resolution, and applications to a broad range of synthetically important asymmetric transformations. This Perspective describes the evolution of this ligand class from Quinap, the first member of the family, to the most recent UCD-Phim/StackPhim analogues, a journey with many “twists and turns”.

中文翻译：

---

轴向手性P，N-配体：最近的一些曲折

轴向手性P，N-配体随着时间的流逝已经成为一种强大的配体类别，在其合成，拆分和广泛应用于合成上重要的不对称转化方面，最近有了重大进展。该观点描述了这种配体类别从家族的第一个成员奎纳普到最近的UCD-Phim / StackPhim类似物的进化，经历了许多“扭曲和转折”。