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Genetics and biobanks converge to resolve a vexing knowledge gap in diabetes
The Lancet Diabetes & Endocrinology ( IF 44.5 ) Pub Date : 2017-11-30 , DOI: 10.1016/s2213-8587(17)30399-6
Jose C Florez

First page of articleThe outdated designations of type 1 diabetes as “juvenile-onset diabetes” and type 2 diabetes as “adult-onset diabetes” reflect the incorrect categorical paradigm that has hindered the ability of clinicians to correctly diagnose outlier cases, causing unnecessary delays in instituting the appropriate therapy. The age-based distinction between the two most common forms of diabetes has become increasingly blurred, as type 2 diabetes becomes more frequent at younger ages and autoimmune diabetes in adulthood is better recognised.

中文翻译:

遗传学和生物库的融合解决了糖尿病中令人烦恼的知识鸿沟

文章首页1型糖尿病过时的命名为“少年发病型糖尿病”和2型糖尿病为“成人发病型糖尿病”,这反映了错误的分类范式,这阻碍了临床医生正确诊断异常病例的能力,从而导致不必要的延迟,无法适当地建立适当的病例。治疗。两种最常见形式的糖尿病之间的基于年龄的区分变得越来越模糊,因为2型糖尿病在年轻时变得更加常见,并且成年后的自身免疫性糖尿病得到了更好的认识。
更新日期:2018-01-24
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