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RNA takes over control of DNA break repair.
Nature Cell Biology ( IF 21.3 ) Pub Date : 2017-Nov-29 , DOI: 10.1038/ncb3645
Francesca Storici , Ailone E. Tichon

Small RNAs generated at DNA break sites are implicated in mammalian DNA repair. Now, a study shows that following the formation of DNA double-strand breaks, bidirectional transcription events adjacent to the break generate small RNAs that trigger the DNA damage response by local RNA:RNA interactions.

中文翻译:

RNA接管DNA断裂修复的控制。

在DNA断裂位点产生的小RNA与哺乳动物DNA修复有关。现在,一项研究表明,在形成DNA双链断裂后,与断裂相邻的双向转录事件会产生小的RNA,这些RNA会通过局部RNA:RNA相互作用触发DNA损伤反应。
更新日期:2017-11-29
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