An opening for humor in melancholy

An opening for humor in melancholy, Published online: 28 November 2017; doi:10.1038/s41593-017-0015-y

A leaky blood–brain barrier may contribute to neuropsychiatric disease. Chronic stress is shown to alter blood–brain barrier permeability, allowing an inflammatory response to penetrate the brain. The deficit is mostly around the nucleus accumbens, an area central to motivation. The affected animals exhibit features of depression.

中文翻译：

---

忧郁中幽默的开放

忧郁中幽默的开放

忧郁的幽默开场，在线发布：2017年11月28日；doi：10.1038 / s41593-017-0015-y

渗漏的血脑屏障可能会导致神经精神疾病。慢性应激被证明会改变血脑屏障的通透性，从而使炎症反应渗透到大脑中。缺陷主要在伏隔核周围，这是动力的中心区域。受影响的动物表现出抑郁的特征。