The teratogenicity of the pesticide nereistoxin (NTX) and its derivative thiocyclam (THI) towards aquatic life was dramatically constrained by a synthetic nanoreceptor, cucurbit[7]uril, through selective encapsulation of the pesticides (K_CB[7]‐NTX of 3.24(±0.31)×10⁶ m⁻¹ and K_CB[7]‐THI of 7.46(±0.10)×10⁵ m⁻¹), as evidenced by the rate of hatchability, morphology development, and tyrosinase activity of zebrafish larvae incubated with the pesticides (3–300 μm) in the absence and in the presence of 300 μm cucurbit[7]uril, demonstrating the significant potential of the nanoreceptor in managing ecological pollution of these pesticides.

中文翻译：

---

合成纳米受体限制农药污染的致畸性

通过选择性包封农药，合成纳米受体葫芦[7] uril极大地限制了农药神经毒素（NTX）及其衍生物噻菌灵（THI）对水生生物的致畸性（K _{CB [7] -NTX}为3.24（ ±0.31）×10 ⁶  m ^-1和K _{CB [7] -THI}为7.46（±0.10）×10 ⁵  m ^-1），如斑马鱼幼体与之一起孵化的孵化率，形态发育和酪氨酸酶活性所证明农药（3-300μ米在不存在和在300μ存在下）米 葫芦[7] uril，证明了纳米受体在控制这些农药的生态污染方面具有巨大潜力。