The biological diversity of ubiquitination resides in the multivalent nature of linkage-specific homotypic and heterotypic ubiquitin (Ub) chains. A recent publication by Yau et al. in Cell describes the development of K11/K48-bispecific antibodies and a physiological role for K11/K48 heterotypic chains in regulation of the cell cycle and clearance of aggregated proteins.

中文翻译：

---

异型泛素链：眼见为实

泛素化的生物学多样性在于连接特异性同型和异型泛素（Ub）链的多价性质。Yau等人的最新出版物。在细胞描述K11 / K48-双特异性抗体的发展和在细胞周期调节K11 / K48异型链的生理作用和聚集的蛋白质的清除。