Tackling host–circuit give and take

Tackling host–circuit give and take, Published online: 24 November 2017; doi:10.1038/s41564-017-0058-6

The incorporation of additional gene circuits into hosts can often lead to unpredicted and undesirable behaviours. Recent work has developed a modelling framework that accounts for host–circuit interactions and can predict a variety of phenotypes at both single-cell and population levels.

中文翻译：

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解决主机电路的让与取

解决主机电路的让与取

解决主机电路的问题，在线发布：2017年11月24日；doi：10.1038 / s41564-017-0058-6

将额外的基因电路整合到宿主中通常会导致无法预料的不良行为。最近的工作已经开发出一种模型框架，该框架说明了宿主电路相互作用，并且可以预测单细胞水平和群体水平的多种表型。