Idiopathic REM sleep behaviour disorder and neurodegeneration — an update

Idiopathic REM sleep behaviour disorder and neurodegeneration — an update, Published online: 24 November 2017; doi:10.1038/nrneurol.2017.157

Idiopathic rapid eye movement (REM) sleep behavioural disorder (RBD) is now recognized as an early marker of α-synucleinopathies. Here, Högl and colleagues review potential biomarkers for RBD and summarize the evidence for a prodromal stage, which might enable disease-modifying intervention. In light of these advances, they reconceptualize idiopathic RBD as isolated RBD.

中文翻译：

---

特发性REM睡眠行为障碍和神经退行性变—最新动态

特发性REM睡眠行为障碍和神经退行性变—最新动态

特发性REM睡眠行为障碍和神经退行性疾病—更新，在线发布：2017年11月24日；doi：10.1038 / nrneurol.2017.157

特发性快速眼动（REM）睡眠行为障碍（RBD）现在被认为是α-突触核蛋白病的早期标志。在这里，Högl及其同事回顾了RBD的潜在生物标志物，并总结了前驱阶段的证据，这可能有助于减轻疾病的干预作用。鉴于这些进展，他们将概念性RBD重新概念化为孤立的RBD。