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Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics
Human Reproduction Update ( IF 13.3 ) Pub Date : 2017-11-23 , DOI: 10.1093/humupd/dmx032
Md Soriful Islam , Andrea Ciavattini , Felice Petraglia , Mario Castellucci , Pasquapina Ciarmela

Uterine leiomyoma (also known as fibroid or myoma) is the most common benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can produce serious clinical symptoms, including excessive uterine bleeding, pelvic pain or pressure, infertility and pregnancy complications. Due to lack of effective medical treatments surgery has been a definitive choice for the management of this tumor.

中文翻译:

子宫平滑肌瘤发病机制中的细胞外基质:未来治疗的潜在目标

子宫平滑肌瘤(也称为肌瘤或肌瘤)是在育龄妇女中发现的最常见的子宫良性肿瘤。它通常不会致命,但会产生严重的临床症状,包括子宫过度出血,骨盆疼痛或压迫,不育和妊娠并发症。由于缺乏有效的药物治疗,外科手术已成为治疗该肿瘤的明确选择。
更新日期:2017-11-23
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