Hydrogen sulfide (H₂S) is one of the most crucial gas signaling agents that mediate many physiological and pathological processes. However, rapid high-efficiency detection and imaging of H₂S in living cells is very challenging. Herein we reported a simple fluorescent nanoprobe using FAM-DNA/AgNP nanocomposites for fast and sensitive H₂S detection based on surface silver displacement. In contrast to the conventional principles for fluorescence turn-on analyte detection, the present work demonstrated a sensitive and selective AgNP based optosensor for the assay of H₂S. Compared with the majority of the reported H₂S probes, complex synthesis procedures and costly equipment are not involved in this assay.

中文翻译：

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基于蚀刻的荧光探针可灵敏地检测细胞中的硫化氢

硫化氢（H ₂ S）是介导许多生理和病理过程的最关键的气体信号传递剂之一。然而，活细胞中H ₂ S的快速高效检测和成像非常具有挑战性。在这里，我们报道了一种简单的荧光纳米探针，该探针使用FAM-DNA / AgNP纳米复合材料基于表面银的位移进行快速，灵敏的H ₂ S检测。与此相反的常规原则荧光开启分析物检测，目前的工作证实了H的测定法的灵敏的和选择性的AgNP基于式光传感器₂ S.与大多数的报道相比ħ ₂小号探针，复杂的合成方法和昂贵的设备不参与此测定。