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Palladium Catalyzed C−C and C−N Bond Formation via ortho C−H Activation and Decarboxylative Strategy: A Practical Approach towards N-Acylated Indoles
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2017-11-22 04:36:18 , DOI: 10.1002/adsc.201700872
Saurabh Kumar 1 , Rahul Singh 1 , Krishna Nand Singh 1
Affiliation  

A concerted palladium catalyzed C−H activation and decarboxylative strategy has been explored for the efficient synthesis of N-acylated indoles. The process allows a facile step- and atom-economic assembly of 3-arylated indole ring from inexpensive and readily available anilides and cinnamic acids as reacting partners.

中文翻译:

钯通过邻位C-H活化和脱羧策略催化C-C和C-N键形成:一种N-酰化吲哚的实用方法

为有效合成N-酰化的吲哚,人们探索了一种协同的钯催化的CH活化和脱羧策略。该方法允许以廉价且容易获得的酸酐和肉桂酸作为反应伙伴,容易地以步骤和原子经济的方式组装3-芳基化的吲哚环。
更新日期:2017-11-22
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