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Functional Cellular Mimics for the Spatiotemporal Control of Multiple Enzymatic Cascade Reactions
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2017-11-22 04:06:02 , DOI: 10.1002/anie.201708826
Xiaoling Liu 1, 2 , Petr Formanek 1 , Brigitte Voit 1, 2 , Dietmar Appelhans 1
Affiliation  

Metabolism mimicry in cell mimics: Multicompartmentalized systems containing pH-responsive Ada-polymersomes as organelle mimics were developed. These systems were employed as cell mimics to mimic metabolism by incorporating various stimuli for regulating enzymatic cascade reactions and for controlling the simultaneous and/or subsequent release of the encapsulated (therapeutic) molecules.

中文翻译:

功能性细胞模拟物的多个酶级联反应的时空控制。

细胞模拟物中的代谢模拟:开发了包含pH响应Ada-多聚体作为细胞器模拟物的多室系统。通过掺入各种刺激物来调节酶促级联反应并控制包封的(治疗性)分子的同时和/或随后释放,这些系统被用作细胞模拟物来模拟新陈代谢。
更新日期:2017-11-22
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