当前位置: X-MOL 学术Biomater. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Targeted tumor SPECT/CT dual mode imaging using multifunctional RGD-modified low generation dendrimer-entrapped gold nanoparticles
Biomaterials Science ( IF 6.6 ) Pub Date : 2017-10-03 00:00:00 , DOI: 10.1039/c7bm00826k
Xiaoying Xu 1, 2, 3, 4, 5 , Lingzhou Zhao 6, 7, 8, 9, 10 , Xin Li 1, 2, 3, 4, 5 , Peng Wang 1, 2, 3, 4, 5 , Jinhua Zhao 6, 7, 8, 9, 10 , Xiangyang Shi 1, 2, 3, 4, 5 , Mingwu Shen 1, 2, 3, 4, 5
Affiliation  

Multifunctional low-generation dendrimer-entrapped gold nanoparticles (Au DENPs) were designed and synthesized. The formed Au DENPs modified with an arginine–glycine–aspartic peptide and labeled with 99mTc possess a uniform size distribution, desirable colloidal stability and biocompatibility, and can be used as a promising nanoprobe for targeted SPECT/CT imaging of αvβ3 integrin-expressing tumors.

中文翻译:

使用多功能RGD修饰的低代树状聚合物包裹金纳米颗粒靶向肿瘤SPECT / CT双模成像

设计并合成了多功能的低代树状聚合物包裹金纳米颗粒(Au DENPs)。所形成的Au DENPs改性用精氨酸-甘氨酸-天冬氨酸肽,并用标记的99米锝具有均匀的粒度分布,可取的胶体稳定性和生物相容性,并且可以用作用于α的有针对性的SPECT / CT成像的有前途的纳米探针v β 3整联表达肿瘤。
更新日期:2017-11-22
down
wechat
bug