N-Alkyl amines are extensively applied in the synthesis of functional materials, pharmaceuticals, and pesticides. The reaction of diols with amines is attractive and has been investigated for more than 30 years by using iridium, ruthenium, and other catalysts. However, the main products with diols as starting materials, especially for C₄–C₆ diols, are N-heterocyclic compounds because cyclization reaction is favorable in thermodynamics. Here, for the first time, a simple and non-noble catalyst CuNiAlO_x prepared by a coprecipitation method was developed for the reaction of C₄–C₆ diols with amines to give monoamination products. This method offers an efficient and environmentally friendly method for the selective monoamination of diols.

中文翻译：

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二醇的可持续催化胺化：从环化到单胺化

N-烷基胺广泛用于功能材料，药物和农药的合成。二醇与胺的反应很有吸引力，并且已经通过使用铱，钌和其他催化剂进行了30多年的研究。但是，以二醇为原料的主要产品，特别是对于C ₄ -C ₆二醇，是N-杂环化合物，因为环化反应在热力学上是有利的。在此，首次开发了一种通过共沉淀法制备的简单且非贵重的催化剂CuNiAlO _x用于C ₄ -C ₆的反应。二醇与胺一起生成单胺化产物。该方法为二醇的选择性单胺化提供了一种有效且环保的方法。