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Development of a Sensitive Microarray Platform for the Ranking of Galectin Inhibitors: Identification of a Selective Galectin-3 Inhibitor
ChemBioChem ( IF 3.2 ) Pub Date : 2017-11-20 03:34:33 , DOI: 10.1002/cbic.201700544 Johann Dion 1 , Tamara Advedissian 2 , Nataliya Storozhylova 1 , Samir Dahbi 1 , Annie Lambert 1 , Frédérique Deshayes 2 , Mireille Viguier 2 , Charles Tellier 1 , Françoise Poirier 2 , Stéphane Téletchéa 1 , Christophe Dussouy 1 , Hiroaki Tateno 3 , Jun Hirabayashi 3 , Cyrille Grandjean 1
ChemBioChem ( IF 3.2 ) Pub Date : 2017-11-20 03:34:33 , DOI: 10.1002/cbic.201700544 Johann Dion 1 , Tamara Advedissian 2 , Nataliya Storozhylova 1 , Samir Dahbi 1 , Annie Lambert 1 , Frédérique Deshayes 2 , Mireille Viguier 2 , Charles Tellier 1 , Françoise Poirier 2 , Stéphane Téletchéa 1 , Christophe Dussouy 1 , Hiroaki Tateno 3 , Jun Hirabayashi 3 , Cyrille Grandjean 1
Affiliation
Sweet screening: A glycan microarray based on evanescent-field fluorescence-assisted detection is used to determine the potency of lactosamine derivatives towards galectins in inhibition experiments and leads to the discovery of a selective galectin-3 inhibitor.
中文翻译:
半乳糖凝集素抑制剂的排名的敏感的微阵列平台的发展:选择性半乳糖凝集素3抑制剂的鉴定。
甜筛选:基于:逝场荧光辅助检测的聚糖微阵列用于确定抑制实验中乳糖胺衍生物对半乳糖凝集素的效力,并导致发现选择性半乳糖凝集素3抑制剂。
更新日期:2017-11-20
中文翻译:
半乳糖凝集素抑制剂的排名的敏感的微阵列平台的发展:选择性半乳糖凝集素3抑制剂的鉴定。
甜筛选:基于:逝场荧光辅助检测的聚糖微阵列用于确定抑制实验中乳糖胺衍生物对半乳糖凝集素的效力,并导致发现选择性半乳糖凝集素3抑制剂。