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Microglia and macrophages in brain homeostasis and disease
Nature Reviews Immunology ( IF 100.3 ) Pub Date : 2017-11-20 , DOI: 10.1038/nri.2017.125
Qingyun Li,Ben A. Barres

Microglia and macrophages in brain homeostasis and disease

Microglia and macrophages in brain homeostasis and disease, Published online: 20 November 2017; doi:10.1038/nri.2017.125

This Review describes recent advances in our understanding of the ontogeny, development and function of brain-resident macrophages and microglia, including their normal functions during brain development and homeostasis and how disturbance of these functions may precipitate neurodegenerative and neuropsychiatric diseases.


中文翻译:

小胶质细胞和巨噬细胞在脑稳态和疾病中的作用

小胶质细胞和巨噬细胞在脑稳态和疾病中的作用

脑稳态和疾病中的小胶质细胞和巨噬细胞,在线发布:2017年11月20日;doi:10.1038 / nri.2017.125

这篇综述描述了我们对驻留于脑的巨噬细胞和小胶质细胞的发育,发育和功能的最新进展,包括它们在大脑发育和体内平衡过程中的正常功能,以及这些功能的紊乱如何导致神经退行性疾病和神经精神疾病。
更新日期:2017-11-20
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