To the Editor Lyerly et al¹ refer to historical aspects of the rubella vaccination program as “a cautionary tale about caution” with lessons pertinent to ongoing Zika vaccine research. However, the US rubella vaccination program has been a tale of appropriate caution and remarkable success in the elimination of rubella and congenital rubella syndrome.² We concur with the authors in their assertions that safety studies in pregnant women are important and that these could have overcome the initial reluctance to give rubella vaccine to women of childbearing age (WCBA). However, further points within the article warrant comment.

中文翻译：

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风疹疫苗—适当谨慎和成功的故事

编者Lyerly等[ ¹ ]将风疹疫苗接种计划的历史方面称为“关于谨慎的警告性故事”，其中包括与正在进行的寨卡疫苗研究有关的经验教训。但是，美国风疹疫苗接种计划一直是一个谨慎的故事，在消除风疹和先天性风疹综合症方面取得了显著成功。²我们同意作者的观点，即对孕妇的安全性研究很重要，而且这些研究本来可以克服最初对育龄妇女（WCBA）接种风疹疫苗的不愿。但是，本文中的其他要点值得评论。