当前位置: X-MOL 学术Analyst › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Chemical analysis in saliva and the search for salivary biomarkers – a tutorial review
Analyst ( IF 4.2 ) Pub Date : 2017-11-03 00:00:00 , DOI: 10.1039/c7an01571b
Kamonwad Ngamchuea 1, 2, 3, 4, 5 , Korbua Chaisiwamongkhol 1, 2, 3, 4, 5 , Christopher Batchelor-McAuley 1, 2, 3, 4, 5 , Richard G. Compton 1, 2, 3, 4, 5
Affiliation  

Biomarkers refer to analytes that can be used in the diagnosis of diseases or disorders. In saliva, there are many components that are potential biomarkers, and increasing research has focussed on the development of saliva as a diagnostic fluid. This review summarizes the existing uses of salivary biomarkers and highlights the importance of the choice of saliva collection as well as the storage procedures. A case study on the effect of collection tools on the concentrations of one of the potential biomarkers, glutathione, is highlighted. Moreover, molecular diagnosis requires reliable measurement assays. This review presents electroanalytical methods for the detection of salivary biomarkers. It further reviews approaches that can be taken to improve the selectivity of electroanalytical assays without the use of biologically selective materials, notably without the use of enzymes or antibodies.

中文翻译:

唾液中的化学分析和唾液生物标志物的搜索-教程复习

生物标志物是指可用于疾病或病症诊断的分析物。在唾液中,有许多成分是潜在的生物标志物,并且越来越多的研究集中在唾液作为诊断液的开发上。这篇综述总结了唾液生物标志物的现有用途,并强调了选择唾液收集以及储存程序的重要性。重点研究了收集工具对一种潜在生物标志物谷胱甘肽浓度的影响的案例研究。此外,分子诊断需要可靠的测量分析。这篇综述介绍了检测唾液生物标志物的电分析方法。它进一步回顾了可在不使用生物选择性材料的情况下提高电分析测定选择性的方法,
更新日期:2017-11-19
down
wechat
bug