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AgSbF6-Catalyzed Tandem Reaction of 2-Alkynylanilines with Cyclic Enynones: Efficient access to 3-Furo[3,2-c]chromenylindoles and Related Scaffolds
Asian Journal of Organic Chemistry ( IF 2.7 ) Pub Date : 2017-11-17 05:25:28 , DOI: 10.1002/ajoc.201700511
Anuradha Dagar 1 , Soumitra Guin 1 , Sampak Samanta 1
Affiliation  

Silver catalysis: A mild and efficient method has been developed for the direct synthesis of a series of 2-substituted-3-furo[2,3-c]chromenyl/tetrahydrobenzofuranyl indoles in good to high chemical yields by performing the tandem heterocyclization reaction between 2-alkynylanilines and 3-alkynyl-4H-chromen-4-ones/2-phenylethynylcyclohex-2-enone in the presence of 2.0 mol % of AgSbF6 as a Lewis acid catalyst.

中文翻译:

AgSbF6催化的2-炔基苯胺与环烯酮的串联反应:有效获得3-Furo [3,2-c]苯并吲哚及其相关骨架

银催化:已开发出一种温和有效的方法,该方法可通过以下反应进行串联杂环反应来直接合成一系列具有良好或高化学收率的2-取代-3-呋喃[2,3- c ]苯并四氢苯并呋喃基吲哚。在2.0摩尔%的作为路易斯酸催化剂的AgSbF 6的存在下,2-炔基苯胺和3-炔基-4 H-铬烯-4-酮/ 2-苯基乙炔基环己基-2-烯酮。
更新日期:2017-11-17
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