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Conservation demands safe gene drive
PLOS Biology ( IF 9.8 ) Pub Date : 2017-11-16 , DOI: 10.1371/journal.pbio.2003850
Kevin M. Esvelt , Neil J. Gemmell

Interest in developing gene drive systems to control invasive species is growing, with New Zealand reportedly considering the nascent technology as a way to locally eliminate the mammalian pests that threaten its unique flora and fauna. If gene drives successfully eradicated these invasive populations, many would rejoice, but what are the possible consequences? Here, we explore the risk of accidental spread posed by self-propagating gene drive technologies, highlight new gene drive designs that might achieve better outcomes, and explain why we need open and international discussions concerning a technology that could have global ramifications.



中文翻译:

保护需要安全的基因驱动

对开发控制入侵物种的基因驱动系统的兴趣正在增长,据报道,新西兰考虑将新生技术作为一种局部消灭威胁其独特动植物的哺乳动物害虫的方法。如果基因驱动成功消除了这些侵入性种群,许多人将为之欢欣鼓舞,但是可能带来的后果是什么?在这里,我们探讨了自我传播的基因驱动技术带来的意外传播风险,重点介绍了可能取得更好结果的新基因驱动设计,并解释了为什么我们需要就可能具有全球影响的技术进行公开和国际讨论。

更新日期:2017-12-01
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