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The NLRP3 inflammasome in acute myocardial infarction
Nature Reviews Cardiology ( IF 49.6 ) Pub Date : 2017-11-16 , DOI: 10.1038/nrcardio.2017.161
Stefano Toldo , Antonio Abbate

The NLRP3 inflammasome in acute myocardial infarction

The NLRP3 inflammasome in acute myocardial infarction, Published online: 16 November 2017; doi:10.1038/nrcardio.2017.161

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Ischaemic injury during an acute myocardial infarction (AMI) event is followed by an intense inflammatory response that occurs after reperfusion. The inflammasome is a protein complex involved in the regulation of this inflammatory response. In this Review, Toldo and Abbate summarize evidence supporting the therapeutic value of inflammasome-targeted strategies in the context of AMI.

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中文翻译:

急性心肌梗死中的NLRP3炎性小体

急性心肌梗死中的NLRP3炎性小体

急性心肌梗死中的NLRP3炎性小体,在线发布:2017年11月16日; doi:10.1038 / nrcardio.2017.161

NatureArticleSnippet(type = short-summary,markup =

急性心肌梗塞(AMI)事件期间的缺血性损伤之后是再灌注后发生的强烈炎症反应。炎性小体是一种蛋白质复合物,参与调节这种炎症反应。在本综述中,Toldo和Abbate总结了支持以炎性体为靶点的策略在AMI中具有治疗价值的证据。

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更新日期:2017-11-16
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