Quid Pro quo: Multidimensional NMR spectroscopy was used to quantify cis-Pro peptide bond fractions in three unfolded proteins. The cis values are systematically lower than those in the corresponding short peptides; this is attributed to reduced conformational entropy in the antiparallel segments preceding and following the cis-Pro peptide bonds and to electrostatic attraction between oppositely charged termini in unblocked peptides.

中文翻译：

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折叠蛋白中顺式脯氨酸形成的倾向

Quid Pro：多维NMR光谱用于定量三种未折叠蛋白中的顺式-Pro肽键部分。的顺式值是系统地低于那些在相应的短肽; 这归因于顺式-Pro肽键之前和之后的反平行区段中构象熵的降低，以及未阻断肽中带相反电荷的末端之间的静电吸引。