Fluorescence imaging, especially specific organelle imaging, has become a significant technology to comprehending cell transplantation, migration, division, fusion, and lysis. In this paper, we designed and synthesized a water soluble and fluorescent polymer named as Poly(AA-TPA-d), which was pH-responsive by the fluorescence channel due to the presence of poly acrylic acid as the polymer backbone. The research results demonstrated that Poly(AA-TPA-d) exhibits novel aggregation-induced-emission (AIE) property. Additionally, due to the hydrogen bond formation and C=O···π interactions between methyl acrylate groups, Poly(AA-TPA-d) was of excellent hydrogel formation ability. Moreover, Poly(AA-TPA-d) displayed good bio-compatibility with the living MPC5 cells and highly specific cytoplasm-targeting ability by MTT assay and cell staining experiment respectively.

荧光成像，尤其是特定的细胞器成像，已成为理解细胞移植，迁移，分裂，融合和裂解的一项重要技术。在本文中，我们设计并合成了一种水溶性和荧光聚合物，称为Poly（AA-TPA-d），由于存在聚丙烯酸作为聚合物主链，该荧光聚合物通过荧光通道具有pH响应。研究结果表明，聚（AA-TPA-d）具有新颖的聚集诱导发射（AIE）特性。另外，由于形成氢键和丙烯酸甲酯基团之间的C ＝ O··π相互作用，聚（AA-TPA-d）具有优异的水凝胶形成能力。而且，