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A single-cell survey of the small intestinal epithelium
Nature ( IF 64.8 ) Pub Date : 2017-11-08 00:00:00 , DOI: 10.1038/nature24489
Adam L. Haber , Moshe Biton , Noga Rogel , Rebecca H. Herbst , Karthik Shekhar , Christopher Smillie , Grace Burgin , Toni M. Delorey , Michael R. Howitt , Yarden Katz , Itay Tirosh , Semir Beyaz , Danielle Dionne , Mei Zhang , Raktima Raychowdhury , Wendy S. Garrett , Orit Rozenblatt-Rosen , Hai Ning Shi , Omer Yilmaz , Ramnik J. Xavier , Aviv Regev

Intestinal epithelial cells absorb nutrients, respond to microbes, function as a barrier and help to coordinate immune responses. Here we report profiling of 53,193 individual epithelial cells from the small intestine and organoids of mice, which enabled the identification and characterization of previously unknown subtypes

中文翻译:

小肠上皮细胞的单细胞检查

肠上皮细胞吸收营养,对微生物作出反应,充当屏障并帮助协调免疫反应。在这里,我们报告从小鼠的小肠和类器官中的53193个单个上皮细胞的概况分析,从而能够鉴定和表征先前未知的亚型
更新日期:2017-11-16
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