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Caenorhabditis elegans as an Emerging Model for Virus-Host Interactions
Journal of Virology ( IF 5.4 ) Pub Date : 2017-12-01 , DOI: 10.1128/jvi.00509-17
Don B. Gammon 1
Affiliation  

Since 1999, Caenorhabditis elegans has been extensively used to study microbe-host interactions due to its simple culture, genetic tractability, and susceptibility to numerous bacterial and fungal pathogens. In contrast, virus studies have been hampered by a lack of convenient virus infection models in nematodes. The recent discovery of a natural viral pathogen of C. elegans and development of diverse artificial infection models are providing new opportunities to explore virus-host interplay in this powerful model organism.



中文翻译:

秀丽隐杆线虫作为病毒-宿主相互作用的新兴模型。

自1999年以来,秀丽隐杆线虫由于其简单的培养,遗传易处理性以及对多种细菌和真菌病原体的敏感性,已被广泛用于研究微生物与宿主之间的相互作用。相反,由于线虫缺乏便利的病毒感染模型,病毒研究受到了阻碍。秀丽隐杆线虫的天然病毒病原体的最新发现和多种人工感染模型的发展,为探索这种强大的模型生物中病毒与宿主之间的相互作用提供了新的机会。

更新日期:2017-11-15
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