A novel procedure to fabricate quaternized cellulose triacetate reverse osmosis (QCTA-RO) membranes via the etherification procedure between partially hydrolyzed CTA-RO membrane and 3-chloro-2-hydroxypropyl-trimethyl ammonium chloride (CHPTAC) in alkaline solutions (pH = 9–11) for different reaction time (1, 2, 3 and 4 h) was proposed. The structure and performances of the obtained QCTA-RO membranes were characterized and their antibacterial performances against E. coli and S. aureus were evaluated through colony counting method. The results showed that quaternary amine group was successfully grafted on the surface of membrane via covalently bond without significant damage to morphology, mechanical performance and thermal stability. The permeation flux values increased with prolonging modification time to 3 h, while the salt rejection decreased slightly but remained above 92%. QCTA-RO membranes displayed good antibacterial activity against Gram-negative E. coli and Gram-positive S. aureus and their bactericidal rates were 78.7–89.0% and 64.7–76.6% respectively at the optimized modification time of 2–3 h.

通过部分水解的CTA-RO膜与3-氯-2-羟丙基-三甲基氯化铵（CHPTAC）在碱性溶液（pH  =  9– 11）提出了针对不同的反应时间（1、2、3和4 小时）的建议。表征了所获得的QCTA-RO膜的结构和性能，以及它们对大肠杆菌和金黄色葡萄球菌的抗菌性能。通过菌落计数法进行评估。结果表明，季胺基团通过共价键成功地接枝到了膜的表面，而对形态，机械性能和热稳定性没有明显的损害。渗透通量值随改性时间延长至3  h而增加，而脱盐率略有下降，但仍保持在92％以上。QCTA-RO膜对革兰氏阴性大肠杆菌和革兰氏阳性金黄色葡萄球菌显示出良好的抗菌活性，在2–3  h的最佳修饰时间，它们的杀菌率分别为78.7–89.0％和64.7–76.6％。