Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes,Analyst

当前位置： X-MOL 学术 › Analyst › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes
Analyst ( IF 4.2 ) Pub Date : 2017-11-08 00:00:00 , DOI: 10.1039/c7an01629h
Kyle L. Fort _{1,

2,

3,

4,

5} , Michiel van de Waterbeemd _{1,

2,

3,

4,

5} , Dmitriy Boll _{6,

7,

8} , Maria Reinhardt-Szyba _{6,

7,

8} , Mikhail E. Belov _{6,

7,

8} , Eita Sasaki _{9,

10,

11,

12} , Reinhard Zschoche _{9,

10,

11,

12} , Donald Hilvert _{9,

10,

11,

12} , Alexander A. Makarov _{1,

2,

3,

4,

5} , Albert J. R. Heck _{1,

2,

3,

4,

5}

Affiliation

Native mass spectrometry can provide insight into the structure of macromolecular biological systems. As analytes under investigation get larger and more complex, instrument capabilities need to be advanced. Herein, modifications to an Orbitrap Q Exactive Plus mass spectrometer that increase signal intensity, mass resolution, and maximum m/z measurable are described.

中文翻译：

在基于Orbitrap的质谱仪上扩展结构分析功能，以处理大型高分子复合物

天然质谱可以洞察大分子生物学系统的结构。随着研究中的分析物变得越来越大和越来越复杂，仪器功能需要提高。在此，描述了对Orbitrap Q Exactive Plus质谱仪的修改，该修改增加了信号强度，质量分辨率和可测量的最大m / z。

更新日期：2017-11-15

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>