An optical sensor based on carbon quantum dots (CQDs) coated with molecularly imprinted polymers (MIPs) was fabricated for selective and sensitive determination of promethazine hydrochloride (PrHy). Water-soluble and fluorescent CQDs were synthesized by a simple, low cost and green approach using orange juice as a carbon source. The special advantage of the synthesized CQDs with this method is low toxicity. The surface of the CQDs was covered with MIPs matrix (CQDs-MIPs) via sol-gel polymerization. For characterization of the CQDs and CQDs-MIPs, UV–vis absorption spectroscopy, fluorescence spectroscopy, dynamic light scattering technique, X-ray diffraction technique, Fourier transform infrared spectroscopy, and transmission electron microscopy were used. The fluorescence intensity of CQDs-MIPs exhibited linear response with the concentration of PrHy in the range from 2.0 to 250 μmol L⁻¹ with a detection limit of 0.5 μmol L⁻¹. The reproducibility of the method was checked for 20 μmol L⁻¹ of PrHy, and the results showed RSD% as 5.1. This sensor was used for determination of PrHy in real samples and showed satisfactory results.

制造了一种基于碳量子点（CQD）的光学传感器，该碳传感器涂覆有分子印迹聚合物（MIP），用于选择性，灵敏地测定盐酸异丙嗪（PrHy）。使用橙汁作为碳源，通过简单，低成本和绿色的方法合成了水溶性和荧光CQD。用这种方法合成的CQD的特殊优势是低毒性。CQD的表面通过溶胶-凝胶聚合反应被MIPs基质（CQDs-MIPs）覆盖。为了表征CQD和CQDs-MIP，使用了紫外可见吸收光谱，荧光光谱，动态光散射技术，X射线衍射技术，傅立叶变换红外光谱和透射电子显微镜。^-1的检出限为0.5μmolL ^-1。检查该方法在20μmolL ^-1 PrHy的重现性，结果显示RSD％为5.1。该传感器用于实际样品中PrHy的测定，结果令人满意。