A novel venlafaxine conjugate V-TDS-G was designed and synthesized in this work. The evaluation in vivo demonstrated that V-TDS-G had an improved targeting ability, which indicated that the G-TDS could act as a vector to enhance the delivery of CNS drugs into brain.

中文翻译：

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GLUT1介导的文拉法辛-硫胺素二硫化物系统-葡萄糖结合物具有“锁定”功能，可用于中枢神经系统递送

本文设计并合成了一种新型文拉法辛偶联物V-TDS-G。体内评估表明，V-TDS-G具有改善的靶向能力，这表明G-TDS可以充当载体来增强CNS药物向大脑的传递。