Paper-based analytical devices introduce an innovative platform technology for fluid handling and analysis, with wide range of applications, promoting low cost, ease of fabrication/operation and equipment independence. This review gives a general overview on the fabrication techniques reported to date, revealing and discussing their weak points as well as the newest approaches in order to overtake current mass production limitations and therefore commercialisation. Moreover, this review aims especially to highlight novel technologies appearing in literature for the effective handling and controlling of fluids. The lack of flow control is the main problem of paper-based analytical devices, which generates obstacles for marketing and slows down the transition of paper devices from the laboratory into the consumers' hands.

中文翻译：

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面向商业化的微流体纸基分析装置综述

纸基分析设备引入了一种用于流体处理和分析的创新平台技术，具有广泛的应用，促进低成本、易于制造/操作和设备独立。本综述概述了迄今为止报道的制造技术，揭示和讨论了它们的弱点以及最新方法，以克服当前的大规模生产限制，从而实现商业化。此外，本综述旨在特别强调文献中出现的有效处理和控制流体的新技术。缺乏流量控制是纸质分析设备的主要问题，这给营销带来了障碍，并减缓了纸质设备从实验室到消费者手中的过渡。