Abstract

A protocol has been developed to achieve selective and direct synthesis of α-iodoketones under mild condition, from the reaction of aminoalkynols with iodine monochloride. The scope of the reaction was investigated using various aminoalkynols with iodine monochloride and the corresponding α-iodoketones were obtained selectively without forming iodocyclized and/or addition products.

A protocol has been developed to achieve selective and direct synthesis of α-iodoketones under mild condition, from the reaction of aminoalkynols with iodine monochloride. The scope of the reaction was investigated using various aminoalkynols with iodine monochloride and the corresponding α-iodoketones were obtained selectively without forming iodocyclized and/or addition products.

中文翻译：

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一氯化碘对氨基炔醇中α-碘酮的高度选择性方法

摘要

从氨基炔醇与一氯化碘的反应中，已经开发出一种在温和条件下实现选择性和直接合成α-碘酮的方案。使用各种氨基炔醇与一氯化碘研究反应的范围，并选择性地获得相应的α-碘酮，而不会形成碘化和/或加成产物。

从氨基炔醇与一氯化碘的反应中，已经开发出一种在温和条件下实现选择性和直接合成α-碘酮的方案。使用各种氨基炔醇与一氯化碘研究反应的范围，并选择性地获得相应的α-碘酮，而不会形成碘化和/或加成产物。