In this work, the first application of core-shell poly(dopamine) magnetic nanoparticles as sorbent for the extraction of a group of eleven phthalic acid esters of interest (i.e. diethyl phthalate (DEP), dipropyl phthalate (DPP), dibutyl phthalate (DBP), bis-isopentyl phthalate (DIPP), bis-n-pentyl phthalate (DNPP), benzylbutyl phthalate (BBP), dicyclohexyl phthalate (DCHP), di-(2-ethylhexyl) phthalate (DEHP), di-n-octyl phthalate (DNOP), diisononyl phthalate (DINP) and diisodecyl phthalate (DIDP)) and one adipate (bis (2-ethylhexyl) adipate, DEHA) from different water samples (Milli-Q, mineral, tap, pond and waste water) is proposed. Analysis were carried out by gas chromatography triple quadrupole tandem mass spectrometry. Parameters that affect the extraction performance were optimized following a step by step approach, being the optimum conditions the extraction of water at pH 6, with 60 mg of sorbent and the elution with 6 mL of dichloromethane. The methodology was validated for the five selected water samples using DBP-d₄ as internal standard. Determination coefficients of matrix-matched calibration curves were above 0.9904 in all cases while relative recovery values ranged between 71 and 120%, with relative standard deviation values below 19%. The limits of quantification of the method ranged between 9 and 20 ng/L. Matrix effects were found for most analytes and water samples. Real water samples were also analyzed, finding DEP and DBP at concentrations below 4.20 and 1.23 μg/L, respectively, in mineral, tap and waste water. DCHP, DEHP and BBP were also found in some of the samples at concentrations below the LOQs of the method.

在这项工作中，首次将核-壳聚（多巴胺）磁性纳米颗粒用作吸附剂，以萃取一组11种目标邻苯二甲酸酯（即邻苯二甲酸二乙酯（DEP），邻苯二甲酸二丙酯（DPP），邻苯二甲酸二丁酯（DBP） ），双-异戊基邻苯二甲酸酯（DIPP），双- ñ -戊基邻苯二甲酸酯（DNPP），邻苯二甲酸苄丁酯（BBP），邻苯二甲酸二环己（DCHP），二- （2-乙基己基）邻苯二甲酸酯（DEHP），二- ñ-邻苯二甲酸二辛酯（DNOP），邻苯二甲酸二异壬酯（DINP）和邻苯二甲酸二异癸酯（DIDP））和一种己二酸酯（己二酸二（2-乙基己基）己二酸酯，DEHA），分别来自不同的水样（Milli-Q，矿物质，自来水，水，池塘和废水）的提议。通过气相色谱三重四极杆串联质谱法进行分析。按照分步方法优化影响萃取性能的参数，这是最佳条件，条件是用60 mg吸附剂萃取pH为6的水，并用6 mL二氯甲烷洗脱。使用DBP-d ₄对5个选定的水样品进行了方法学验证作为内部标准。在所有情况下，基质匹配的校准曲线的测定系数均高于0.9904，而相对回收率值介于71％至120％之间，相对标准偏差值低于19％。该方法的定量限为9至20 ng / L。对于大多数分析物和水样品，发现基质效应。还对真实水样进行了分析，发现矿物质，自来水和废水中的DEP和DBP的浓度分别低于4.20和1.23μg/ L。在某些样品中还发现DCHP，DEHP和BBP的浓度低于该方法的最低定量限。