Rational design of proteins that exchange on functional timescales,Nature Chemical Biology

当前位置： X-MOL 学术 › Nat. Chem. Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Rational design of proteins that exchange on functional timescales
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2017-10-23 , DOI: 10.1038/nchembio.2503
James A Davey , Adam M Damry , Natalie K Goto , Roberto A Chica

Rational design of proteins that exchange on functional timescales

Rational design of proteins that exchange on functional timescales, Published online: 23 October 2017; doi:10.1038/nchembio.2503

NatureArticleSnippet(type=short-summary, markup=

The development of a computational protein design method, meta-multistate design, enables the design and validation of protein variants termed DANCERs that spontaneously exchange between predicted conformational states on the millisecond timescale.

, isJats=true)

中文翻译：