Maternal immune activation (MIA) during pregnancy is associated with an increased risk of behavioral disorders in the offspring of affected mothers. Two recent studies highlight how maternal inflammation disrupts inhibitory interneuron networks and suggest that the maternal gut microbiome may be a contributing risk factor for MIA-induced behavioral abnormalities.

中文翻译：

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炎症和自闭症：从母体肠到胎儿脑

怀孕期间的母体免疫激活（MIA）与患病母亲后代行为障碍的风险增加相关。最近的两项研究突出了孕产妇炎症如何破坏抑制性神经元网络，并表明孕产妇肠道微生物组可能是MIA引起的行为异常的重要危险因素。