The prevalence of antimicrobial-resistant pathogens has highlighted the urgent need for new drugs. Actinomycetes have been the most prominent sources of natural products for drug discovery and development. Advances in genomics have inspired several emerging strategies to reinvigorate the field of natural product discovery, especially in actinomycete-derived natural products.

中文翻译：

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基因组学驱动的放线菌天然产物发现

抗菌素耐药病原体的流行凸显了对新药的迫切需求。放线菌一直是用于药物发现和开发的天然产物的最主要来源。基因组学的进步激发了几种新兴战略，以重振天然产物的发现领域，特别是在放线菌来源的天然产物中。