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Severe asthma: looking beyond the amount of medication
The Lancet Respiratory Medicine ( IF 76.2 ) Pub Date : 2017-10-11 , DOI: 10.1016/s2213-2600(17)30379-x
Andrew Bush , Sejal Saglani , Louise Fleming

First page of articleIn 20081 we proposed the concept of problematic severe asthma as an umbrella term for children referred to a specialist service who are not responding to high-dose asthma medications.2 Problematic severe asthma comprised non-asthma-related conditions (ie, wrong diagnosis) and asthma-plus comorbidities (eg, obesity, rhinosinusitis, food allergies, and dysfunctional breathing; excluding gastro-oesophageal reflux).3 After confirming the diagnosis, all children with problematic severe asthma referred to our severe asthma clinic undergo a detailed nurse-led assessment,4 which considers airway disease in the context of comorbidities, and social and environmental factors,5 before even considering assessment of airway pathology using bronchoscopy.

中文翻译:

严重哮喘:超出药物治疗范围

文章首页在2008年1中,我们提出了有问题的严重哮喘的概念,作为对转介对大剂量哮喘药物没有反应的专科服务的儿童的总称。2有问题的严重哮喘包括与哮喘无关的疾病(即,错误的诊断)和哮喘加合并症(例如,肥胖,鼻-鼻窦炎,食物过敏和呼吸功能障碍;不包括胃食管反流)。3确认诊断后,所有转诊至我们严重哮喘诊所的有严重哮喘问题的儿童均接受了由护士指导的详细评估,4该评估在合并症,社会和环境因素的背景下考虑了气道疾病,5 甚至在考虑使用支气管镜评估气道病理之前。
更新日期:2017-11-10
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