当前位置: X-MOL 学术J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Synthesis of Polysubstituted Pyrroles through a Formal [4 + 1] Cycloaddition/E1cb Elimination/Aromatization Sequence of Sulfur Ylides and α,β-Unsaturated Imines
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2017-11-09 00:00:00 , DOI: 10.1021/acs.joc.7b01931
Bei-Yi Cheng 1 , Ya-Ni Wang 1 , Tian-Ren Li 1 , Liang-Qiu Lu 1 , Wen-Jing Xiao 1, 2
Affiliation  

A reaction sequence comprising a formal [4 + 1] cycloaddition, an E1cb elimination, and an aromatization process is described in this work. By doing so, polysubstituted pyrroles were achieved from easily available chemicals, sulfur ylides, and α,β-unsaturated imines. This protocol features mild conditions, high efficiency, and wide substrate scopes.

中文翻译:

通过形式的[4 +1]环加成/ E1cb消除/芳香化的硫叶立德和α,β-不饱和亚胺合成多取代的吡咯

这项工作描述了包括正式的[4 +1]环加成,E1cb消除和芳构化过程的反应序列。通过这样做,从容易获得的化学物质,硫酰化物和α,β-不饱和亚胺获得了多取代的吡咯。该协议具有温和的条件,高效率和广泛的底物范围。
更新日期:2017-11-09
down
wechat
bug