All living organisms emit, detect, and respond to chemical stimuli, thus creating an almost limitless number of interactions by means of chemical signals. Technological and intellectual advances in the last two decades have enabled chemical signals analyses at several molecular levels, including gene expression, molecular diversity, and receptor affinity. These advances have also deepened our understanding of nature to encompass interactions at multiple organism levels across different taxa. This tutorial review describes the most recent analytical developments in ‘omics’ technologies (i.e., genomics, transcriptomics, proteomics, and metabolomics) and provide recent examples of its application in studies of chemical signals. We highlight how studies have integrated an enormous amount of information generated from different omics disciplines into one publicly available platform. In addition, we stress the importance of considering different signal modalities and an evolutionary perspective to establish a comprehensive understanding of chemical communication.

中文翻译：

---

用于分析生态相互作用中化学信号的综合组学视角†

所有活生物体都会发出，检测并响应化学刺激，从而通过化学信号产生几乎无限数量的相互作用。在过去的二十年中，技术和智力上的进步使得能够在几个分子水平上进行化学信号分析，包括基因表达，分子多样性和受体亲和力。这些进步也加深了我们对自然的理解，以涵盖不同分类群中多种生物水平的相互作用。本教程回顾描述了“组学”技术（即，基因组学，转录组学，蛋白质组学和代谢组学），并提供其在化学信号研究中的最新应用实例。我们重点介绍研究如何将来自不同的组学学科的大量信息整合到一个公开可用的平台中。此外，我们强调了考虑不同信号模式和进化观点以建立对化学通讯的全面理解的重要性。