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Tranexamic acid: is it about time?
The Lancet ( IF 168.9 ) Pub Date : 2017-11-07 , DOI: 10.1016/s0140-6736(17)32806-4
David J Dries

For decades, the antifibrinolytic drug tranexamic acid has been used for indications such as dental extractions in patients with haemophilia. Additionally, tranexamic acid has been widely used, although not routinely across the world, to reduce blood loss in surgery. More recently, the potential of tranexamic acid in trauma and post-partum haemorrhage has been of interest.1 In two large, randomised controlled trials, CRASH-22 and WOMAN,3 tranexamic acid reduced mortality from bleeding in patients with these conditions.

中文翻译:

氨甲环酸:时间到了吗?

数十年来,抗纤溶药物氨甲环酸已被用于适应症,例如血友病患者的拔牙。另外,氨甲环酸已被广泛使用,尽管在世界范围内不是常规用途,以减少手术中的失血量。最近,氨甲环酸在创伤和产后出血中的潜力引起了人们的兴趣。1在两项大型随机对照试验CRASH-2 2和WOMAN中,氨甲环酸3降低了患有这些疾病的患者因出血引起的死亡率。
更新日期:2018-01-12
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