Collagen is the primary protein component in mammalian connective tissues. Over the last 20 years, evidence has mounted that collagen matrices exhibit substantial heterogeneity in their hierarchical structures and that this heterogeneity plays important roles in both structure and function. Herein, an overview of studies addressing the nanoscale compositional and structural heterogeneity is provided and connected to work exploring the mechanical implications for a number of tissues.

中文翻译：

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胶原结构和组成异质性与组织力学性能的关系：化学的角度。

胶原蛋白是哺乳动物结缔组织中的主要蛋白质成分。在过去的20年中，越来越多的证据表明胶原蛋白基质在其层次结构中显示出很大的异质性，并且这种异质性在结构和功能上都起着重要的作用。在此，提供了针对纳米级组成和结构异质性的研究概述，并将其与探索多种组织的机械意义的工作联系在一起。