Peptide sciences developed dramatically as a result of routine use of solid‐phase peptide synthesis and nowadays offer a rich set of well‐established strategies to design and identify functional peptide sequences for advanced applications in materials sciences. Appropriate sequences for a wide range of interesting material targets, ranging from molecules to materials surfaces and internal interfaces, can be selected via combinatorial means, and sequence specificities within the resulting peptide–target interactions can be routinely investigated. Based on this understanding, macromolecular sciences can define new polymer structures that meet required functionalities or functional sequences with fully synthetic, nonpeptidic precision polymers to endeavor toward information‐based design of next‐generation, purpose‐adapted macromolecules.

中文翻译：

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鉴定功能性肽序列以指导精密聚合物的设计

固相肽合成的常规使用使肽科学得到了飞速发展，如今，提供了一套完善的策略来设计和鉴定功能性肽序列，以用于材料科学的高级应用。可以通过组合方式选择从分子到材料表面和内部界面的各种有趣的材料靶标的合适序列，并且可以常规地研究所得肽-靶标相互作用中的序列特异性。基于这种理解，大分子科学可以定义新的聚合物结构，以完全合成的非肽精密聚合物满足所需的功能性或功能序列，从而努力进行基于信息的下一代专用大分子设计。