Task-specific dystonia is a movement disorder characterized by a painless loss of dexterity specific to a particular motor skill. This disorder is prevalent among writers, musicians, dancers and athletes. No current treatment is predictably effective, and the disorder generally ends the careers of affected individuals. Traditional disease models of dystonia have a number of limitations with regard to task-specific dystonia. We therefore discuss emerging evidence that the disorder has its origins within normal compensatory mechanisms of a healthy motor system in which the representation and reproduction of motor skill are disrupted. We describe how risk factors for task-specific dystonia can be stratified and translated into mechanisms of dysfunctional motor control. The proposed model aims to define new directions for experimental research and stimulate therapeutic advances for this highly disabling disorder.

中文翻译：

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针对特定任务的肌张力障碍的统一运动控制框架

特定于任务的肌张力障碍是一种运动障碍，其特征在于无痛地丧失了特定运动技能所特有的敏捷性。这种疾病在作家，音乐家，舞者和运动员中普遍存在。目前尚无可预测的有效治疗方法，该疾病通常会终止受影响个体的职业生涯。关于特定任务的肌张力障碍，传统的肌张力障碍疾病模型具有许多局限性。因此，我们讨论了新兴证据，表明该疾病的根源是健康运动系统的正常补偿机制，其中运动技能的表示和再现受到干扰。我们描述了如何针对特定任务的肌张力障碍的危险因素进行分层并将其转化为运动控制功能障碍的机制。