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Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions
Nature Materials ( IF 41.2 ) Pub Date : 2017-11-06 , DOI: 10.1038/nmat5006
Hideki Nakamura , Albert A. Lee , Ali Sobhi Afshar , Shigeki Watanabe , Elmer Rho , Shiva Razavi , Allister Suarez , Yu-Chun Lin , Makoto Tanigawa , Brian Huang , Robert DeRose , Diana Bobb , William Hong , Sandra B. Gabelli , John Goutsias , Takanari Inoue

Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions

Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions, Published online: 06 November 2017; doi:10.1038/nmat5006

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An approach to form protein-based hydrogels in living cells that resemble physiological hydrogel-like size-dependent molecular sieves is presented. Synthetic RNA granules mimics are obtained by functionalizing these entities with RNA-binding motifs.

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中文翻译:

通过多价分子相互作用在细胞内生产水凝胶和合成RNA颗粒

通过多价分子相互作用在细胞内生产水凝胶和合成RNA颗粒

通过多价分子相互作用在细胞内生产水凝胶和合成RNA颗粒,在线发布:2017年11月6日; doi:10.1038 / nmat5006

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提出了一种在活细胞中形成基于蛋白质的水凝胶的方法,该方法类似于生理性水凝胶样尺寸依赖性分子筛。合成的RNA颗粒模拟物是通过使用RNA结合基序对这些实体进行功能化而获得的。

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更新日期:2017-11-06
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