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A Two-Photon Luminescent Dye-Loaded Metal-Organic Framework for Physiological Temperature Sensing within Biological Windows.
ChemPlusChem ( IF 3.4 ) Pub Date : 2017-11-01 , DOI: 10.1002/cplu.201700438
Yating Wan 1 , Tifeng Xia 1 , Yuanjing Cui 1 , Yu Yang 1 , Guodong Qian 1
Affiliation  

Luminescent temperature sensing in biological windows is uniquely superior compared to traditional temperature sensing methods because the scattering and absorption by skin, tissue and blood is minimal. In this study, the two-photon luminescence from dyes loaded into a metal-organic framework was utilised to achieve physiological temperature sensing within two biological windows. A composite was prepared that can be excited at 1064 nm to emit at 650 nm, well within the two biological windows. The two-photon luminescence intensity at 650 nm has a linear relationship with temperature over the range 20 to 60 °C. In addition, the stability and quantum efficiency were significantly improved after loading into the MOF and, with high temperature resolution, excellent repeatability and low biological toxicity, measurements with this composite has great potential to be applied to physiological temperature sensing in cells or tissues.

中文翻译:

用于在生物窗口内进行生理温度感测的两光子发光染料加载的金属有机框架。

与传统的温度感测方法相比,生物窗口中的发光温度感测具有独特的优势,因为皮肤,组织和血液的散射和吸收极少。在这项研究中,利用加载到金属有机框架中的染料的双光子发光来实现两个生物窗口内的生理温度感测。制备了可以在两个生物学窗口之内的,可以在1064 nm激发,在650 nm发射的复合材料。650 nm处的双光子发光强度与温度在20至60°C范围内具有线性关系。此外,装入MOF后,稳定性和量子效率得到了显着提高,并且具有较高的温度分辨率,出色的可重复性和较低的生物毒性,
更新日期:2017-11-06
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