Alternative polyadenylation (APA) is emerging as a major post-transcriptional mechanism for gene regulation, and dysregulation of APA contributes to several human diseases. However, the functional consequences of APA in human cancer are not fully understood. Particularly, there is no large-scale analysis in cancer cell lines.

中文翻译：

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人癌症中其他聚腺苷酸化的全面表征

替代的聚腺苷酸化（APA）正在成为基因调控的主要转录后机制，APA的失调会导致多种人类疾病。但是，APA在人类癌症中的功能后果尚不完全清楚。特别地，在癌细胞系中没有大规模的分析。