Sugars have pathogenic roles in diabetes. In Nature Medicine, Zhang et al. revisit this dogma and show that mannose induces the generation of regulatory T (Treg) cells. The immunoregulatory effect of mannose not only prevented the onset of autoimmune diabetes but also blocked disease progression in new-onset diabetic mice.

中文翻译：

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糖尿病的甜蜜交易

糖在糖尿病中具有致病作用。在《自然医学》中，Zhang 等人。重新审视这个教条并表明甘露糖诱导调节性 T (Treg) 细胞的产生。甘露糖的免疫调节作用不仅可以预防自身免疫性糖尿病的发作，还可以阻止新发糖尿病小鼠的疾病进展。