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Metabolic Imaging of Infection
The Journal of Nuclear Medicine ( IF 9.3 ) Pub Date : 2017-11-01 , DOI: 10.2967/jnumed.117.191635
Ismaheel Lawal , JanRijn Zeevaart , Thomas Ebenhan , Alfred Ankrah , Mariza Vorster , Hendrik G. Kruger , Thavendran Govender , Mike Sathekge

Metabolic imaging has come to occupy a prominent place in the diagnosis and management of microbial infection. Molecular probes available for infection imaging have undergone a rapid evolution starting with nonspecific agents that accumulate similarly in infection, sterile inflammation, and neoplastic tissue and then extending to more targeted probes that seek to identify specific microbial species. This focus review describes the metabolic and molecular imaging techniques currently available for clinical use in infection imaging and those that have demonstrated promising results in preclinical studies with the potential for clinical applications.



中文翻译:

感染的代谢成像

代谢成像已在微生物感染的诊断和管理中占据重要位置。可用于感染成像的分子探针已经迅速发展,从在感染,无菌炎症和赘生性组织中类似积累的非特异性试剂开始,然后扩展到旨在鉴定特定微生物物种的更具针对性的探针。这篇重点综述描述了目前可用于感染成像的临床上使用的代谢和分子成像技术,以及那些在临床前研究中显示出有希望的结果并具有临床应用潜力的技术。

更新日期:2017-11-01
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